Irbesartan+ Hydrochlorothiazide is indicated for the treatment of hypertension
Irbesartan belongs to a class of drugs called angiotensin receptor blockers (ARBs). Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict), which leads to an increase in blood pressure (hypertension). By blocking the action of angiotensin, Irbesartan dilates blood vessels and reduces blood pressure. Hydrochlorothiazide is a thiazide diuretic. It exerts its antihypertensive effects by inhibiting Na+/Cl? reabsorption from the distal convoluted tubules in the kidney. By reducing osmotic pressure in this way, Hydrochlorothiazide reduces the reabsorption of water in the distal convoluted tubules and thereby reduces plasma volume and cardiac output. The combined effect of these actions is to reduce BP.
Irbesartan+ Hydrochlorothiazide 300mg+12.5mg Tablet:
Irbesartan+ Hydrochlorothiazide 150mg+12.5mg