BRAND NAME:
Nysa

GENERIC NAME:
Piroxicam beta cyclodextrin

THERAPEUTIC SEGMENT:
Non steroidal anti inflammatory drug

INDICATIONS:
Acute painful conditions
Rheumatoid arthritis
Osteo-arthritis
Ankylosing spondylitis
Musculoskeletal and joint disorders
Gout
Post-operative pain

BRIEF DESCRIPTION:
Chemically Piroxicam is described as 4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-1, 2 benzothiazine-3-carboxamide-1, 1-dioxide and the molecular formula is C15 H13 N3 O4S
NYSA (Piroxicam beta-cyclodextrin) is the first non steroidal anti inflammatory agent, which also possesses analgesic and antipyretic properties, in which the active substance is complexed with the cyclic oligosaccharide cyclodextrin which acts as artificial receptor. The beta cyclodextrin acts like a molecular size capsule that envelopes the poorly soluble Piroxicam and improve its solubility and speeds absorption. This offers the potential advantage of a more rapid onset of effects and better tolerability due to reduced contact time with the GI mucosa. Piroxicam achieves Peak plasma level in 30 to 60 minutes after oral dose while beta cyclodextrin is not absorbed in the colon and metabolized to various sugars. Half life of Piroxicam is 50 hours. Piroxicam excreted mainly through urine with smaller amount in faeces.

DOSAGE FORM:
Tablets 20mg

PACK SIZE:
20’s